![]() And then you know you have to set them up and then you have to say ‘Oh by the way I am gay.’ And it’s like well why?” Introducing a character because of their sexuality felt a little bit too pandering. Why don’t we change his sexual orientation because that would be good to do that with a character we already know. ![]() Simon Pegg explained the decision on SiruisXM radio. Sulu is shown in a relationship with another man and having a daughter. If Goldsman and company do intend to pursue this it wouldn’t be too surprising and follows Star Trek’s retconning of Hikaru Sulu into a gay man in director Justin Lin and writer Simon Pegg’s Star Trek: Beyond film. Daniel Richtman #BlackLivesMatter June 13, 2020 Heard they are toying with the idea of making Kirk bi in the new series The rumor comes from scooper Daniel Richtman who wrote on Twitter, “Heard they are toying with the idea of making Kirk bi in the new series.” Kirk in the show as well as making him bisexual. While Goldsman indicated the show would embrace more “classical” ‘Trek’ values” a new rumor details Goldsman and company are tossing around the idea of including James T. Related: Akiva Goldsman Discusses His Vision For Star Trek: Strange New Worlds He elaborated, “I imagine it to be closer to the original series than even ‘DS9.'” But I think our plots will be more closed-ended than you’ve seen in either ‘Discovery’ or ‘Picard.'” ![]() He went on to explain how the show will embrace episodic storytelling, “Obviously, we will take advantage of the serialized nature of character and story building. ![]() Photo Cr: Ben Mark Holzberg/CBS© 2018 CBS Interactive. “New Eden” - Ep #202 – Pictured: Anson Mount as Captain Pike of the CBS All Access series STAR TREK: DISCOVERY. ![]()
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![]() ![]() Cite them in your publications if OpenPose helps your research! (Links and more details in the Citation section below). OpenPose papers published in IEEE TPAMI and CVPR.E.g., adding your custom inputs, pre-processing, post-posprocessing, and output steps.įor further details, check the major released features and release notes docs. C++ API and Python API for custom functionality.Command-line demo for built-in functionality.Hardware compatibility: CUDA (Nvidia GPU), OpenCL (AMD GPU), and non-GPU (CPU-only) versions. ), keypoints as array class, and support to add your own custom output code (e.g., some fancy UI). Output: Basic image + keypoint display/saving (PNG, JPG, AVI. Input: Image, video, webcam, Flir/Point Grey, IP camera, and support to add your own custom input source (e.g., depth camera). Single-person tracking for further speedup or visual smoothing.Calibration toolbox: Estimation of distortion, intrinsic, and extrinsic camera parameters.Compatible with Flir/Point Grey cameras.Synchronization of Flir cameras handled.3D triangulation from multiple single views.3D real-time single-person keypoint detection:.See OpenPose Training for a runtime invariant alternative. Runtime depends on number of detected people. 2x21-keypoint hand keypoint estimation.Runtime invariant to number of detected people. 15, 18 or 25-keypoint body/foot keypoint estimation, including 6 foot keypoints.2D real-time multi-person keypoint detection:.The OpenPose runtime is constant, while the runtime of Alpha-Pose and Mask R-CNN grow linearly with the number of people. We show an inference time comparison between the 3 available pose estimation libraries (same hardware and conditions): OpenPose, Alpha-Pose (fast Pytorch version), and Mask R-CNN. Tianyi Zhao and Ginés Hidalgo testing the OpenPose Unity Plugin Runtime Analysis Tianyi Zhao testing the OpenPose 3D Module Unity Plugin (Center and right) Authors Ginés Hidalgo and Tomas Simon testing face and hands Whole-body 3D Pose Reconstruction and Estimation Testing OpenPose: (Left) Crazy Uptown Funk flashmob in Sydney video sequence. Results Whole-body (Body, Foot, Face, and Hands) 2D Pose Estimation ![]() We would also like to thank all the people who has helped OpenPose in any way.Īuthors Ginés Hidalgo (left) and Hanbyul Joo (right) in front of the CMU Panoptic Studio Contents OpenPose would not be possible without the CMU Panoptic Studio dataset. It is maintained by Ginés Hidalgo and Yaadhav Raaj. It is authored by Ginés Hidalgo, Zhe Cao, Tomas Simon, Shih-En Wei, Yaadhav Raaj, Hanbyul Joo, and Yaser Sheikh. OpenPose has represented the first real-time multi-person system to jointly detect human body, hand, facial, and foot keypoints (in total 135 keypoints) on single images. ![]() ![]() ![]() I don’t know how deep they are, but the water in them looks stagnant and a little gross, so don’t fall in. Upon climbing into Peek-A-Boo, you will come across to small potholes that I’ve found filled with water each time I’ve gone. When the sandstone is wet and muddy, it make climbing up more challenging. Many times, especially after a rain, there can be a pool of water in front of the entrance. It sounds harder than it is, and is even easier if you have someone to give you a boost. You’ll know that you’re at the beginning of Peek-A-Boo by seeing foot holds carved into sandstone that aids in climbing a 20 foot wall to reach the slot. Two natural bridges found in Peek-A-Boo Gulchįrom the bottom of wash, as mentioned before, you’ll see the Dry Fork Narrows entrance to the left, and if you head right, (east) Peek-A-Boo Gulch is about 100 yards down the wash on north side. In some places the slot canyon is less than 18 inches wide. I am 6’1, 175lbs, and it was a VERY tight squeeze for me in some parts. One of the things that you must know is that these are some of the tightest slot canyons you’ll find, especially Spooky and Brimstone Gulch. The left fork then heads in a northwest direction for one mile, which will end at parking area which can fit about 12-15 cars. The dirt road starts heading east and after about 0.7 miles it forks. It is passable for passenger vehicles just take care not to go too fast for ruts can be common. This will take you 1.7 miles to the trailhead. From here you will head southeast on the unpaved Hole in the Rock Road for 26 miles (42 km). From the turnoff onto Hole in the Rock Road would be a good spot to reset your trip odometer to 0. There should be a sign after a curve to the right that says Hole in the Rock Road. ![]() From Torrey, UT, head south on Hwy 12 for nearly 60 miles. If you were to go straight instead of take the curve that would turn into Hole in the Rock Road. Follow Hwy 12 for five miles, and as the highway makes a left curve, the unpaved Hole in the Rock Road will be on the right side of the road. The road will head in a southeastern direction. Season to hike – can be hiked all year long, avoid during July through August due to extreme heat and flash floodsįrom Escalante, Utah, take the main road, Highway 12, east through Escalante. Hike DetailsĮlevation at Peek-A-Boo Gulch – 4720 feetĭifficulty – Moderate, extremely confined spaces, if claustrophobic best to avoid. These three slot canyons are nicely lined up in a neat row, which allows the hiking enthusiast to hike through all three in one afternoon. These slot canyons started as mere cracks and fissures in the sandstone, but over time, flash floods ripped into the cracks, creating the amazing and serpentine slot canyons that we now enjoy. Peek-A-Boo, Spooky, and Brimstone gulches, are just three of the dozens found off of Hole in the Rock Road. Located along Hole in the Rock Road just southeast of Escalante, Utah, are some of the finest slot canyons in the world. Peek-A-Boo Gulch, Spooky Gulch, Brimstone Gulch, and Dry Fork Narrows I would not take a SUV (non stock 4WD) on it as it is almost 50 miles of shake, rattle and roll, and it would definitely not be good for a typical SUV wanna-be 4WD.Īlso - there is almost another 10 days of constant T-Storms forecast for the Spring Mts, so conditions could get worse, but are fine as of. I left the visitor center, cautiously drove to the Mt pass campground, never even had to put it in 4WD.Īll in all, it was a bit more bumpy than when I drove it last Jan 2021, but it is definitely a doable trail with any stock 4WD. He indicated my rig (with 37 inch tires and a 2 inch lift) might have trouble making it up to the desert pass campground due to the severity of the washouts. The nut case (Volunteer) at the Corn Creek visitor center (the same one that still requires masks) tried to tell me the trail was washed out from recent rains and very hazardous. It has rained extensively the past two weeks, lots of thunderstorms in the Spring Mts. I'm driving a Jeep Rubicon 2020JL, 37 inch tires, 2inch lift. ![]() ![]() ![]() Enjoy quick access to everything you need for your next project with the filter feature. The new search feature helps you not only find the correct effects and templates even faster – it also corrects small spelling mistakes. 10 content items/month Subscription savings Audio and video content Rights of use for projects A HASSLE-FREE WORKFLOW Enjoy a host of new features: The program interface is razor-sharp and legible at all times on 4K monitors. Choose favorites Display options Personalized categories Improved thumbnails UNLIMITED POSSIBILITIES As a Photostory deluxe 365 subscription user, you gain full access to a library packed full of music, stock footage, and animations for any application. Achieve professional results faster than ever before thanks to innovative features. This would be compatible with both 32 bit and 64 bit windows.PHOTOSTORY DELUXE 2023: CREATE A PHOTOSTORY QUICK & EASYīRING YOUR AUDIENCE ALONG: THE MOST USER-FRIENDLY WAY TO A BREATHTAKING PHOTOSTORY CREATE IMPRESSIVE SLIDESHOWS EVEN FASTER It's easier than ever to organize and categorize your images. This is complete offline installer and standalone setup for MAGIX Photostory Deluxe 2018. ![]() ![]() MAGIX Photostory Deluxe 2018 Free DownloadĬlick on below button to start MAGIX Photostory Deluxe 2018 Free Download. Processor: 2 GHz Intel Pentium processor or later.Hard Disk Space: 2 GB of free space required.System Requirements For MAGIX Photostory Deluxe 2018īefore you start MAGIX Photostory Deluxe 2018 free download, make sure your PC meets minimum system requirements. Latest Version Release Added On: 17th Dec 2017.Compatibility Architecture: 32 Bit (x86) / 64 Bit (圆4).Setup Type: Offline Installer / Full Standalone Setup.Software Full Name: MAGIX Photostory Deluxe 2018.MAGIX Photostory Deluxe 2018 Technical Setup Details Can add audio and video files into your slideshows.Can add special effects into your slideshows.Can customize the slideshows with different transitions.Got a simple and straightforward user interface.Lets you share the slideshows with friends easily.Handy application for creating impressive slideshows.You can also download adobe Photoshop CC 2017 v18.īelow are some noticeable features which you’ll experience after MAGIX Photostory Deluxe 2018 free download. All in all MAGIX Photostory Deluxe 2018 is a straightforward and simple application which can be used for creating imposing slideshows. Once the slideshow is created you have various different sharing capabilities. Slideshows can also be enhanced by adding audio as well as video files into your project. The slideshows can further be customized by adding various different transitions and it also lets you to add the titles as well as special effects to your slideshows. For editing of your images it will guide you to an external application which is Photo Designer. Apart from creating the slideshows you can also use this tool for making adjustments to your images. One of the panels is dedicated for previewing the slideshow, the 2 nd panel is dedicated for applying different effects and the last panel has been dedicated for managing the added files. MAGIX Photostory Deluxe 2018 has got a very simple and straightforward user interface that has been divided into three different panels. You can also download MAGIX Photostory Deluxe 2017. This application will also let you share the slideshows with your friends and that too in a very easy manner. ![]() MAGIX Photostory Deluxe 2018 is a handy application which can be used for creating some impressive slideshows from your own photos. It is full offline installer standalone setup of MAGIX Photostory Deluxe 2018. MAGIX Photostory Deluxe 2018 Free Download Latest Version for Windows. ![]() ![]() ![]() If you only want to make a copy of the pst file if it has changed, this PowerShell script compares the file size, copying it only if the file size is different. Get-Process Outlook | Foreach-Object | stop-process –forceĬopy-Item "D:\Documents\Outlook Files\*.pst" $TodayFolder New-Item $TodayFolder -ItemType DirectoryĬopy-Item $Env:USERPROFILE"\Documents\Outlook Files\*.pst" $TodayFolderĬlose Outlook, copy the PST files then reopen it after the PST files are copied. $TodayFolder = "D:\PST Backups\$(get-date -f yyyy-MM-dd)" Storing PST files in folders by date reduces clutter if you have multiple PST files and makes it easy to delete old backup sets. This script will work on any computer when you use the default location for the PST files (C:\Users\%username%\Documents\Outlook Files).Ĭopy-Item $Env:USERPROFILE"\Documents\Outlook Files\*.pst" "D:\PST Backups"Ĭreate a subfolder with today's date for the backup location. To copy all the PST file in a specific location, to a backup folder in another location:Ĭopy-Item "C:\Outlook Files\*.pst" "D:\PST Backups" Instead, you should export the calendar and contacts to a CSV or PST file. But, because OST files can only be opened by the account and profile that created the OST file, you need a 3rd party utility to recover content in the OST file if the account was removed from your profile. ![]() One glaring exception: if you use an IMAP account and have Calendar, Contacts, and Tasks folders with "this computer only" in the name, they are not synced with the server. pst file for a list of common issues and solutions.While you can make copies of OST files used by IMAP and Exchange accounts, because an OST is just an offline cache of the mailbox on the server, everything in the OST file is synced. You'll still see and have access to your email, contacts, and calendar in Outlook. ![]() When Outlook exports email, contacts, and calendar info to a. Outlook does not export meta-data such as folder properties ( views, permissions, and AutoArchive settings) message rules and blocked senders lists. Outlook makes a copy of your email to the. Pst files are created when you export or back up email, contacts, and calendar to an Outlook. pst file to your existing Outlook folders. Tip: If you want to retrieve only a few emails or contacts from an Outlook Data File (.pst), you can open the Outlook Data File, and then, in the navigation pane, drag and drop the emails and contacts from. Once your Internet connection is re-established, Outlook will continue importing the. This happens when the Internet connection is interrupted, even for a moment. pst file to your Microsoft 365 mailbox, you may see a message that it's trying to connect with Microsoft 365. When the progress box disappears, the import is finished. Outlook starts importing the contents of your. This imports the data into the folder currently selected.Ĭhoose Finish. If you're NOT importing into your Microsoft 365 mailbox, choose Import items into the current folder. pst file into your Microsoft 365 mailbox, choose that mailbox here. If you're importing the contents of your. If a password was assigned to the Outlook Data File (.pst), enter the password, and then click OK. Under Options, choose how you want to deal with emails and contacts, then choose Next. Select Outlook Data File (.pst) and click Next.īrowse to the. Select Import from another program or file, and then click Next. See What version of Outlook do I have? to find your version of Outlook and to get to right import steps. If your ribbon doesn't have a File option in the top left corner, you aren't using an Outlook app installed on your computer. These instructions assume you've already exported your Outlook email, contacts, and calendar from another instance of Outlook, and now you want to import them to Outlook.Īt the top of your Outlook ribbon, select File. You want to move Outlook items between local folders and an IMAP or Exchange server. ![]() You want to move Outlook items from PC to Mac or Mac to PC You want to move Outlook items from one PC to another PC You want to move Outlook items from one email account to another email account There are several reasons why you might want to import Outlook items from an Outlook Data File (.pst). ![]() ![]() ![]() Tons of content in game, a large amount of it ported from the abandoned game2 project, the rest from Armed Assault or OFP. The performance was bad, the AI was massively overpowered (spotting you through vegetation, buildings and solid terrain at 500 meters) and then got nerfed massively, of the campaign missions there was not a single one that wasn't in some way broken, some weren't fixed until now because of the intensity of the errors (Mortars in Manhattan, loose ends in the final mission.). The fact that they went for fantasy names makes it a little bit harder to relate to them. Cargo planes, planes in general, lots of other stuff) Arma 2 has vehicles for almost every need and situation, Arma 3 doesn´t (e.g. IMHO this makes the old selling point "Arma has everything you could dream off" invalid. In fact BF4 has more unique vehicles than Arma. Arma 2 had 21 fully unique military land vehicles (not counting all the other stuff and all the variants) while those few vehicles in Arma 3 even share some assets (turrets) or simply are copy-pasted (drones, SDVs etc.). Some vehicles were recycled from A1 but they were up to Arma 2 standards and therefore OK. Some Weapons are shared by all factions wich is quite frankly unacceptable.Īrma 2 had all the gear you would expect from USMC, Russian and Ex-Soviet Block forces. The Weapon count is still a bit low though and the fact that most weapons are fictional and come with fantasy names leaves a sour taste. All Factions have their own Standard rifle. Altis seems to run much smooter compared to that.Īrma 3 Weapons are of high quality and come with decent sounds. But I think that Chernaruss had a very heavy impact on performance, especially in Chernogorsk. ![]() Arma 2s SP Missions were much better (exept for freedom fighters, that one is still full of bugs).įiring Drill Missions are a nice thing to try out, but nothing with real replayability or value.īoth Chernarus and Altis are Masterpieces. The Showcase Missions in Arma 3 are pretty mediocre and I sincerely hope that they are not representative of how the campaign will be. but actually I prefer if BIS takes the time to make a good campaign so I´m OK with the decision to postpone the campaign release. The Arma 2 Release (at least in Germany) was full of Bugs, instable, and the MP was laggy as hell. ![]() ![]() Add to cart Norco Rampage 1 20 Black/Green. 2021 Kona Shonky Frame Long 26" Dirt Jumper CrMo Steel Gold Single Speed. Seller assumes all responsibility for this listing. It is equally at home at the bike parks or at local dirt jumps thanks to its full Crmo frame with internal … Vibratory Plate Compactor 14". In addition to Drive, browse our full selection of Parts & Accessories. chainguide / … Get the best deals on Suspension for Dirt Jumper Steel Bicycle Forks when you shop the largest online selection at eBay. It has the Manitou Circus Sport/Comp fork, that came on it from the factory. Top 10 Best Dirt Bike Chain and Sprocket sets 2023. ![]() The hybrid bike also snuck into the list for dirt jump bikes under $500. headset: GW integrated tapered IS42/IS52, sealed bearings. The bike pedals for dirt jumper bikes are available for purchase. ![]() 1 Dirt Jump Bike is ready to take on dirt jumps, pump tracks, street, ramps and more. I'm trying to find a decent bike for under 700 usd. Get the best deals on Steel 1 1/8 in-Threadless Forks for Dirt Jumper Bicycle when you shop the largest online selection at eBay. Not the DJ you know, but the one you want. It is equally at home at the bike parks or at local dirt jumps thanks to its full Crmo frame with internal head tube and a rigid Crmo fork with a suspension-corrected height for future upgrades. Surly Moonder Fork 135mm Non-Offset Black The reach is 400mm for the regular, and 420mm for the long, with a effective top tube length of 585 or 605mm respectively. They also supports a number of independent riders in a range of disciplines.Dirt jumper stel. This includes the Canadian XC Norco Factory Team, the Norco Factory Racing World Cup downhill team, and the UCI-Continental road race team H&R Block Pro Cycling. Norco is involved in the sport of cycling, and cycling generally, through a number of sponsorship initiatives. standout models here are the Volt and the Ares.īikes for children and frame kits are also available. Aluminum and steel options are available. ![]() bikes for high octane, high jumping thrills on the pavement or the dirt.The styles include includes the Aurum,, Sight, Optic, fluid, Bigfoot, and Revolver. bikes that can handle mud, dirt, rocks and other obstacles going uphill, downhill, along the trail or through the air.The range includes the VFR, XFR, Indie, Malahat, Rideau, and Yorkville. bikes designed as alternatives to the car for fitness, commuting, going about everyday activities, and weekend leisure.This range includes Tactic, Valence, Search and Threshold. Norco breaks this down into Race and Endurance Bikes bikes built for racing, long rides and adventure.They also support cycling advocacy programs and employ a number of cycling ambassadors. They continue to produce bikes suitable for everyone from commuters going to work and children going to school, to professional athletes on the road, trail and mountain. Today their bikes are sold internationally. In 1991 the Rampage became the first North American-made mountain bike with front suspension. Norco was also a pioneer in mountain biking, designing its first mountain bike models in 1984 when the style and sport were in their infancy. ![]() It was one of the first manufacturers in North America, for example, to introduce 10 speed road bikes - that was in 1975. It also led the way in other styles of bike. The company's first factory team sponsorship happened 1981 when the Factory BMX Team was formed. This support of BMX continued, with them being part of the developing BMX story. In the early 1970s, for example, it embraced the emerging BMX style of bike, introducing the first ever full suspension version to the Canadian market in 1973. Throughout its more than 50 year history it has had a number of firsts, and has been responsible for various innovations. It is still headquartered there in the city of Port Coquitlam. The company was founded in British Columbia, Canada in 1964. They are a well-known name in the world of cycling because of this range and because of their active involvement, from grassroots cycling up to the top levels of the sport. Today the range that they offer is extensive and includes road, City, Mountain, BMX and street bikes. Since its earliest days Norco has been a brand of bike manufacturer that has embraced new styles, championed new technologies and supported the various cycling disciplines to promote and improve both the sport, and cycling in general. ![]() ![]() ![]() Put a whoopee cushion under your baby’s high-chair cushion, under the booster seat or car seat cover and see if you get a laugh from the baby, his fart-loving older brother or your hubs. After breakfast, hand over their toothbrush - but instead of the usual white paste, opt for something white, creamy and…sweet! Cream cheese or vanilla frosting will do the trick if they use a colored kids’ tooth gel, try using cake decorating gel instead. Surprise your kids this April Fools’ Day with a little toothpaste switcheroo. Obviously if you have younger children, you’ll want to take the balloons out of their room before they drift off to sleep. When they put their head down to sleep, they’ll realize you got the last April Fools’ laugh. ![]() Remove the pillows and fill their pillowcases with several partially inflated balloons. Just when they thought April Fools’ Day was over, here’s one last prank. This is April Fools’ and not Halloween, after all. When the water is turned on, you’ll have colored water! You might want to stay away from red. Use a Q-tip to put gel food coloring around the inside of the faucet in the bathtub or sink. Offer up brownies as an afternoon snack, but everyone will be shocked when they find brown letter “E”s (get it - brown “E”s?) instead! Bathtime hoax Amanda Mushro The hotter the water, the more clear the ice will be when frozen. Add almost boiling water to the ice cube trays and toss in a few plastic bugs. This oldie-but-goodie prank is easy to make at home with this tip. Honk and wave at me!” This joke is even funnier if they get to take a ride in the car with you. Let your practical jokers put a sign on your car that reads “My kids are playing an April Fools’ joke on me. A good option: “You’re going to wash your hands, right?” Roll the toilet paper back up and wait to see who ends up getting the message. Unroll the toilet paper and leave a funny message for the unsuspecting user. Give your kids a laugh at lunchtime by attaching googly eyes to, well, everything. Swap out their underwear drawer for bathing suits for an early morning prank. Juice joke Amanda MushroĪnyone want juice? When your family tries to taking a sip of this juice, they'll find out it’s really Jell-O. When your hungry kids try to dig in, they’ll get quite the surprise. Put cereal and milk in a bowl and let it freeze overnight. If your kids are heavy sleepers, carry them into their sibling’s bed and let them wake up in a different room to start April Fools’ on the right foot. Keep on scrolling for some good old-fashioned fun. Pranksters and prankees alike will get a kick out out of these silly gags. It goes without saying that you should stay away from any pranks that'll bring your kids to tears - unless the tears are from laughing so hard. ![]() ![]() ![]() How Well Do Dogs See?Īll of these features equip a dog to be a good hunter under various light conditions. Even within breeds, the visual streak can vary from type to type. Pugs, for example, have a small spot of sharp vision - an “area centralis” - as humans do. The shorter a breed’s head, the narrower (more circular) the streak tends to be. In dogs with long heads like wolves, the streak is wide, with the nerves evenly distributed. The visual streak varies greatly among breeds, and studies suggest that different breeds see the world differently. The visual streak is a horizontal band in the retina right above the optic nerve this area has the highest concentration of rods and cones, and vision is sharpest here. It’s also what allows them to see in dimmer light. And unlike humans, dogs have a reflective lining behind the retina called the tapetum lucidum it’s what makes dogs’ eyes glow eerily when light hits them. Canine eyes are different than human eyes in that they have a third eyelid called the nictitating membrane, a thin whitish-pink tissue that protects the eye. Dog eyes also contain structures not found in a camera, such as the gel-like vitreous humor that fills the eyeball and gives it shape. As a result, dogs don’t see as many colors as do people. The cones and rods send these signals via the optic nerve to the brain, which constructs an image from them.ĭogs Get Dry Eye Too.Some Breeds More Than OthersĮyes without tears are only for Cameron Diaz in The Holiday.ĭogs have only two types of cones, compared with the three types in human eyes. Light then passes through the cornea and lens, which focus the light on the retina, a layer containing color-sensitive cones and motion- and light-sensitive rods, which convert light into electrical signals. Light enters through the pupil, and the iris controls the amount of light allowed in. To understand eye problems in dogs, it helps to know a little bit about how their eyes function. “Now that I specialize in ophthalmology, I more often see cataracts, glaucoma and retinal disorders.” How Dogs’ Eyes Work Christine Lim, DVM, DACVO, a veterinarian in Chicago. “As a general practitioner, I was often presented with problems such as conjunctivitis, dry eye and corneal ulcer,” says Dr. Some eye disorders occur more often than others (a dog’s breed usually plays a role). If your dog’s eyes have been looking a little red or cloudy lately, or if you’ve noticed they’re pawing at, rubbing, or showing signs of irritation around their eyes, you might need to make an appointment with your vet.Įye problems in dogs are no joke - dogs can suffer from a host of health conditions including glaucoma, conjunctivitis, dry eyes, cataracts and more. It could be something more than cuteness, though. They are the epitome of the “pleading face” emoji. It’s been proven that gazing into your pet’s eyes produces oxytocin and promotes bonding. “Puppy dog eyes” gets dog parents every time. See our privacy statement to find out how we collect and use your data, to contact us with privacy questions or to exercise your personal data rights. ![]() ![]() If use of these CNS depressants in combination with XYWAV is required, dose reduction or discontinuation of one or more CNS depressants (including XYWAV) should be considered. The concurrent use of XYWAV with other CNS depressants, including but not limited to opioid analgesics, benzodiazepines, sedating antidepressants or antipsychotics, sedating anti-epileptic drugs, general anesthetics, muscle relaxants, and/or illicit CNS depressants, may increase the risk of respiratory depression, hypotension, profound sedation, syncope, and death. Warnings and Precautions Central Nervous System Depression in patients with succinic semialdehyde dehydrogenase deficiency.in combination with sedative hypnotics or alcohol and.Abuse or misuse of illicit GHB, either alone or in combination with other CNS depressants, is associated with CNS adverse reactions, including seizure, respiratory depression, decreases in the level of consciousness, coma, and death.īecause of the risks of CNS depression and abuse and misuse, XYWAV is available only through a restricted program under a Risk Evaluation and Mitigation Strategy (REMS) called the XYWAV and XYREM REMS. Abuse and MisuseThe active moiety of XYWAV is oxybate or gamma-hydroxybutyrate (GHB).Many patients who received XYWAV during clinical trials in narcolepsy and idiopathic hypersomnia were receiving CNS stimulants. Clinically significant respiratory depression and obtundation may occur in patients treated with XYWAV at recommended doses. Central Nervous System DepressionXYWAV is a CNS depressant.WARNING: CENTRAL NERVOUS SYSTEM DEPRESSION and ABUSE AND MISUSE. Prevalence of excess sodium intake in the United States-NHANES, 2009-2012. Jackson SL, King SM, Zhao L, Cogswell ME.US Department of Health and Human Services, US Food and Drug Administration website.Palo Alto, CA: Jazz Pharmaceuticals, Inc. Recently approved and upcoming treatments for narcolepsy. Efficacy and safety of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate JZP-258) in a placebo-controlled, double-blind, randomized withdrawal study in adults with narcolepsy with cataplexy. ![]() Bogan RK, Thorpy MJ, Dauvilliers Y, et al.XYWAV ® (calcium, magnesium, potassium, and sodium oxybates).Narcolepsy is complicated by high medical and psychiatric comorbidities: a comparison with the general population. ![]() |
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